Minimum effective local anaesthetic dose for spinal anaesthesia

Minimum effective local anaesthetic dose for spinal anaesthesia.

Editor—In their response 1 to my criticisms 2 of their paper 3 Sell and colleagues accept some of my points, and refute others. On most of the latter we will simply have to agree to differ, but, not surprisingly , I cannot accept their quoting my own review 4 in support of their belief that the solutions which they used were isobaric! Their quote from the article ('Given the normal variation [o...

Minimum effective local anaesthetic dose of isobaric levobupivacaine and ropivacaine administered via a spinal catheter for hip replacement surgery.

BACKGROUND Continuous spinal anaesthesia with spinal catheters allows incremental dosing of local anaesthetic and, consequently, less haemodynamic changes. However, little is known about the required doses. Therefore, we designed a study to assess the minimum effective local anaesthetic dose (MLAD) of levobupivacaine and ropivacaine in this context. METHODS Forty-one patients undergoing hip r...

Ultrasound reduces the minimum effective local anaesthetic volume.

Hyaluronidase reduces local anaesthetic volumes for sub-Tenon's anaesthesia.

BACKGROUND Volumes of local anaesthetics for sub-Tenon's anaesthesia vary. Lower volumes produce less akinesia, whereas higher volumes increase chemosis and intra-ocular pressures. Hyaluronidase is often added to local anaesthetics to improve akinesia without increasing the volume of the injection, but this is controversial. This randomized, sequential allocation study examines the addition of ...

Ultrasound reduces the minimum effective local anaesthetic volume compared with peripheral nerve stimulation for interscalene block.

BACKGROUND Previous studies have demonstrated that lower local anaesthetic (LA) volumes can be used for ultrasound (US)-guided interscalene brachial plexus block (ISB). However, no study has examined whether US can reduce the volume required when compared with nerve stimulation (NS) for ISB. Our aim was to do this by comparing the minimum effective analgesic volumes (MEAVs). METHODS After eth...